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EVALUATION OF ANTIMICROBIAL POTENTIAL OF ETHANOLIC LEAF AND STEM BARK EXTRACTS OF TAMARINDUS INDICA. Agada GOA, Chollom SC, Gotep JG, Gambo NN, Tyem AD, Okeke IO, Nwankiti OO, Okwori AEJ

EVALUATION OF ANTIMICROBIAL POTENTIAL OF ETHANOLIC LEAF AND STEM BARK EXTRACTS OF TAMARINDUS INDICA.

Agada GOA, Chollom SC, Gotep JG, Gambo NN, Tyem AD, Okeke IO, Nwankiti OO, Okwori AEJ

International Journal of Applied Microbiology Science 2012; 1(3): 26-34

Abstract

Ethanolic extracts of two parts of Tamarindus indica plant were evaluated to establish the scientific basis for their ethno-medical application in treatment of certain ailments. The phytochemical constituents of the extracts were analyzed along with their antimicrobial activity against both gram negative and gram-positive bacteria and fungi using the paper disc diffusion method. The extracts were active against both gram positive and gram-negative bacteria. Phytochemical studies revealed the presence of tannins, saponins, alkaloids and flavonoids, while antimicrobial studies of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extracts on the test organisms showed that the lowest MIC and MBC were demonstrated against Salmonella typhi, Staphylococcus aureus, Bacillus subtilis and Yersinia enterocolitica and the highest MIC and MBC were exhibited against Salmonella gallinarum and Pseudomonas aeruginosa. It is hoped that this discovery will draw the attention of scientists to the plant for possible exploration and exploitation towards drug discovery.

Keywords: Antimicrobial activity, minimum bactericidal concentration, minimum inhibitory concentration, Tamarindus indica
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