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PLANT TISSUE CULTURE: AN ALTERNATIVE FOR PRODUCTION OF USEFUL METABOLITE. ALKA, AMIT MONGA, PRAMOD SINGH PATWAL

PLANT TISSUE CULTURE: AN ALTERNATIVE FOR PRODUCTION OF USEFUL METABOLITE.

ALKA, AMIT MONGA, PRAMOD SINGH PATWAL

International Journal of Natural Product Science 2012: Spl Issue 1:187.

Abstract(RBIP-187)

The production of plant metabolites by callus and cell suspension cultures have been carried out on an increasing scale since the end of the 1950's. Since Japan has a highly developed fermentation technology, many industrial companies, in collaboration with some university groups. The Japan Tobacco Inc.'s interest involved around mass-production of tobacco cells as raw materials of cigarettes; the company established 20 kL fermentors which were the largest for plant cells in 1970's. Japan also elucidated the fundamentals of production of Panax ginseng cells in large volumes. Researchers reported that cultured ginseng cells stimulated physiological activities in animals in a similar fashion as elicited by native ginseng roots. In 1982, the 5th International Congress of Plant Tissue and Cell Cultures were held in Japan related to production of secondary metabolites. A number of firms and academic institutions in the U.S., Japan, Canada, and Europe have been investigating intensively the production of a very promising anti-tumor compound, taxol, using this technology.
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