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BROCCOLI: OVERVIEW. Pushpa Sharma, Mayank Tikoo, Suhas Jalali, Priya Masoan

BROCCOLI: OVERVIEW.

Pushpa Sharma, Mayank Tikoo, Suhas Jalali, Priya Masoan

International Journal of Natural Product Science 2012: Spl Issue 1:177.

Abstract(RBIP-177)

In the present study, role of broccoli in management of diabetes has been summarized. Presently this area has undergone an extensive research. Diabetes is the worldwide most common disease nowadays. India is the diabetes capital of the world. Broccoli (brassica oleracea) has been found as an agent, which can help in management of the diabetes mellitus. It contains sulforaphane, (an organosulphur compound) an aliphatic isothiocynate which has an antioxidant property. When broccoli is chewed, it releases glucoraphanin and myrosinase, which works together to produce sulforaphane. High glucose level can cause a threefold increase in ros (reactive oxygen species). ROS are responsible for increase in cystolic calcium concentration which causes rapid destruction of beta cells of islets of langerhans and insulin production is reduced. Sulforaphane activates NRF2 protein which protects cells and tissues from damage by stimulating the phase ii enzymes which detoxify ROS molecules. Sulforaphane reduces ROS by 74% thus reducing damage to beta cells by diabetes mellitus. Thus sulforaphane from broccoli may help reverse the damaging effect of diabetes linked vascular disease. Conclusion: From this we concluded that broccoli has wide potential diverse applications and act on hepatic system for control of diabetes. Broccoli may help reverse the damaging effect of diabetes related vascular disease.
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