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ROLE OF MARKERS IN STANDARDISATION OF HERBAL DRUGS. Aanchal, Harwinder Singh Rao, Dinesh Kumar, Pooja Sharma

ROLE OF MARKERS IN STANDARDISATION OF HERBAL DRUGS.

Aanchal, Harwinder Singh Rao, Dinesh Kumar, Pooja Sharma

International Journal of Natural Product Science 2012: Spl Issue 1:161.

Abstract(RBIP-161)

Herbal drugs are obtained from the natural resources such as plants, animals. These are used for making medicines where the standardization and quality control with proper integration of scientific techniques & traditional knowledge is important. Correct identification and quality control of starting material is an essential preresiquite to ensure reproducibility quality of herbal medicine which contributes to its efficacy. For standardization, the markers are important. The standardization of herbal drugs including authentication of genuine drug , harvesting the best quality raw material , assessment of intermediate and finish product& detection of harmful& toxic ingredient. Specific markers are required for quantitative studies of herbal products. Markers are mainly categorized in two classes: DNA markers and chemical markers.DNA markers are reliable for informative polymorphism as the genetic composition is unique for each species. Chemical markers generally refer to phytochemical constituents including primary and secondary metabolites. DNA markers are used in authentication of medicinal plants and their breeding etc. Chemical markers help in identification of adulterants, confirmation of collection site and quality evaluation and diagnosis of herbal intoxication. Chemical markers are pivotal in the current practice of quality control.
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