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NERIUM OLEANDER-DEADLIEST PLANT OF THE WOLD. Rohit sharma, Pooja Sharma, Dinesh Kumar, Harwinder Singh Rao

NERIUM OLEANDER-DEADLIEST PLANT OF THE WOLD.

Rohit sharma, Pooja Sharma, Dinesh Kumar, Harwinder Singh Rao

International Journal of Natural Product Science 2012: Spl Issue 1:160.

Abstract(RBIP-160)

Nerium oleander (apocynaceae) is an evergreen shrub or small tree, toxic in all its part. It is the most commonly known as oleander. It is one of commonly grown garden plants. Nerium oleander has historically been considered as poisnous plant based on number of its compound. Among these compounds are oleandrin and oleandrigenin known as cardiac glycosides which are known to have narrow therapeutic index and can be toxic when ingested. It is well tolerated up to the 10.2 mg extract/day dosage with few significant side effects. One single leaf could kill an adult human. In 2002, there is a 847 known human poisoning in the united states related to oleander and there are in numerable reported suicidal cases of consuming mashed oleander seeds in the southern India.. There does not appear to be any toxicity associated with exposure of a Nerium oleander extract to the skin. Both animal and human studies suggest that dermal application of Nerium oleander extract is safe. Upon ingestion, shutting down of cardiac vascular and nervous system causing severe nausea and projectile vomiting and Blurred vision etc. In chronic overdose cases diarrhea, depression, loss of appetite are usually seen.
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