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NATURAL HERBS – IN NOVEL DRUG DELIVERY SYSTEM. Aanchal, Dinesh Kumar, Pooja Sharma

NATURAL HERBS – IN NOVEL DRUG DELIVERY SYSTEM.

Aanchal, Dinesh Kumar, Pooja Sharma

International Journal of Natural Product Science 2012: Spl Issue 1:150.

Abstract(RBIP-150)

The use of natural herbs as excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The traditional concept of the excipients as any component other than the active substances which are inert and cheap vehicle to an essential constituent. Excipients are component other than the active substance(s) intentionally added to formulation of dosage form. The herbal excipients are preferred due to lack of toxicity, easy availability and economic consideration as compared to synthetic one. In case of polysaccharides, these are used for the development of solid dosage forms. These are highly stable, hydrophilic in nature. Pectin, starch, gum and amylase are the few examples of polysaccharides used in dosage form. They are useful in targeted delivery system to colon because these polysaccharides remain intact in physiological environment of the stomach but degraded in human colon. Volatile oils are also used which are the mixtures of the hydrocarbons and oxygenated compounds for example menthol improves the bioavailability of the poor water soluble drugs. The herbal excipients are promising biodegradable materials these can chemically compatible with the excipients in novel drug delivery system.
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