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STUDIES ON ANTIDIABTIC ACTIVITY OF AQUESOUS EXTRACT OF LEAVES AND FRUITS OF HOLOPTELIA INTEGRIFOLIA Parminder Kaur, Avninder Singh Mann

STUDIES ON ANTIDIABTIC ACTIVITY OF AQUESOUS EXTRACT OF LEAVES AND FRUITS OF HOLOPTELIA INTEGRIFOLIA

Parminder Kaur, Avninder Singh Mann

International Journal of Natural Product Science 2012: Spl Issue 1:137.


Abstract(RBIP-137)

The purpose to investigate the antidiabetic properties of aqueous extract of the leaves and fruits of Holoptelia integrifolia. Holoptelia integrifolia (Roxb) Planch (ulmaceae) is commonly known as Indian elm, Kanju. In traditionally system of medicine they are used as bitter, astringent, acrid, anti-inflammatory, digestive, carminative, laxative and in rheumatism. The aqueous extract of leaves and fruits of Holoptelia integrifolia was given to rats at doses administered intravenously (I.V.) ranged from 50-60 mg/kg body weight which comparable with glibenclamide used as a refrence drug. The aqueous extracts of leaves and fruits of Holoptelia integrifolia administered at dose of 60 mg/kg. Aqueous extract of leaves produced significant diabetes inhibition when compared with glibenclamide. The result suggested that aqueous extract of leaves of Holoptelia integrifolia showed significant inhibition on diabetic rats.
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