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NANO MEDICINE: DIAGNOSIS, THERAPY AND FOLLOW-UP OF CARDIOVASCULAR DISEASES. Deepak Kalra1, Akash Kalra, Eshant Duggal, Anurag Khatkar

NANO MEDICINE: DIAGNOSIS, THERAPY AND FOLLOW-UP OF CARDIOVASCULAR DISEASES.

Deepak Kalra1, Akash Kalra, Eshant Duggal, Anurag Khatkar


International Journal of Natural Product Science 2012: Spl Issue 1:89.

Abstract (RBIP-89)

Role of Nano medicine in Prevention, Diagnosis and Therapy of Cardiovascular diseases. Cardiovascular diseases remain the most frequent cause of death in the world, according to the World Health Organization, with myocardial infarction and stroke accounting for about half of all deaths. Nano medicine is anticipated to aim for improvements in early diagnosis, acute intervention and follow-up-therapy. Nanometer-sized agents are being preclinically tested that render an unstable plaque visible in magnetic resonance imaging (e.g. Gadomer®, Dendrimer based MRI agent) and at the same time release a drug to stabilize the plaque. Targeted agents could deliver a therapeutic payload, for example a drug that stabilizes the plaque and prevents rupturing. New treatments will include intelligent nanobiomaterials with the ability to attract local adult stem cells or cultured cells to the site of injury, providing cell therapy that should improve heart function and decrease mortality for patients with severe heart insufficiency. Nanomedicines proved to be the promising as far as diagnosis and treatment cardiovascular diseases as well as follow-up. Nanomedicine is a vital area for the research for the early Diagnosis and Prevention of the Cardiovascular Diseases like Stroke and Cardiac insufficiency. Future prospective of the Nanomedicine for cardiovascular diseases is the clinical availability of therapies based on tissue engineering that represents a tremendous step forward in regenerative medicine. By building on the pioneering achievements of tissue engineering, advanced therapies in regenerative medicine can address even more challenging objectives – to initiate and control the regeneration of pathological tissue, and to treat, modify and prevent disabling chronic disorders such as diseases of the cardiovascular system.
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