Wounds are injuries to the skin resulting in its opening or breakage. These may be caused by physical, chemical, thermal, microbial or immunological insult to the tissue. Healing process begins as soon as injury happens.
Wound healing is a complex process that can be broadly divided into three phases
1.Inflammatory phase involves the establishment of homeostasis and inflammation,
2.Proliferate phase involves of granulation, contraction and epithelialisation
3.Remodelling phase which determines the strength and appearance of the healed tissue
Herbs and plants and their extracts have been in use for the treatment & management of wounds since ancient times. To increase the acceptability of ethnic formulations or traditional medicines, these herbs & their extracts must be scientifically evaluated for their bioactivities and possible mechanism of action. If we could validate these herbs/plants, their active components or extracts for their bioactivities, these can be source of new drug molecules.
Ziziphus mauritiana is a spiny evergreen shrub or a small tree, commonly found in the tropical and sub-tropical regions. Its bark and roots contains triterpenoid, zizybernalic acid. In this issue we present research paper on wound healing potential of the plant.